Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6513187 | 0.86 | MEN1 (0.48) | MEN1KMT2A | |
| SCHEMBL6810345 | 0.86 | ALOX5 (0.49) | PTGS2AOC3ALOX5PTGS1 | |
| SCHEMBL6512857 | 0.83 | PTGS2 (0.40) | PTGS2AOC3KDM4EMEN1KMT2A | |
| SCHEMBL6513925 | 0.82 | PTGS2 (0.52) | PTGS2 | |
| SCHEMBL6516441 | 0.82 | MALT1 (0.49) | PTGS2AOC3MEN1KMT2APTGS1 | |
| SCHEMBL6517908 | 0.82 | MALT1 (0.49) | PTGS2AOC3MEN1KMT2A | |
| SCHEMBL6512752 | 0.81 | KDM5A (0.39) | PTGS2KDM4EALDH1A1GHSRMAPT | |
| SCHEMBL6519130 | 0.81 | CHRNA7 (0.54) | PTGS2KDM4EALDH1A1POLBHPGD | |
| SCHEMBL6516327 | 0.81 | PTGS2 (0.43) | PTGS2AOC3GHSRPTGS1 | |
| SCHEMBL6519552 | 0.81 | PTGS2 (0.57) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086097-B1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER (US) | 2004-05-19 | — | — | EP | claimed |