Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811034 | 0.86 | PTGS2 (0.39) | ALOX5PTGS2AOC3PTGS1 | |
| SCHEMBL6514126 | 0.85 | RPA1 (0.52) | ALOX5PTGS2AOC3 | |
| SCHEMBL6513603 | 0.80 | CA9 (0.62) | ALOX5PTGS2 | |
| SCHEMBL6514851 | 0.79 | PTGS2 (0.71) | ALOX5PTGS2PTGS1CYP2C9 | |
| SCHEMBL8422277 | 0.75 | PTGS2 (0.66) | ALOX5PTGS2PTGS1 | |
| SCHEMBL8420104 | 0.75 | PTGS2 (0.54) | ALOX5PTGS2PTGS1 | |
| SCHEMBL859280 | 0.72 | RPA1 (0.60) | PTGS1 | |
| SCHEMBL28808759 | 0.72 | TAAR1 (0.52) | PTGS2 | |
| SCHEMBL6810314 | 0.72 | PTGS2 (0.42) | ALOX5PTGS2PTGS1 | |
| SCHEMBL6517008 | 0.72 | PTGS2 (0.46) | ALOX5PTGS2PTGS1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086097-B1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER (US) | 2004-05-19 | — | — | EP | claimed |