Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KHK | P50053 | 2/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.35 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.35 |
| ▸ | USP28 | Q96RU2 | 2/20 | 0.35 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811374 | 1.00 | HTR2C (0.44) | HTR2CALDH1A1LMNAHSD11B1XIAP | |
| SCHEMBL6808586 | 0.87 | ALDH1A1 (0.44) | HTR2CALDH1A1LMNAHSD11B1XIAP | |
| SCHEMBL6808590 | 0.87 | ALDH1A1 (0.44) | HTR2CALDH1A1LMNAHSD11B1XIAP | |
| SCHEMBL5631645 | 0.84 | XIAP (0.45) | HTR2CALDH1A1LMNAHSD11B1XIAP | |
| SCHEMBL5631643 | 0.84 | XIAP (0.45) | HTR2CALDH1A1LMNAHSD11B1XIAP | |
| SCHEMBL14922244 | 0.84 | ALDH1A1 (0.48) | HTR2CALDH1A1LMNAHSD11B1XIAP | |
| SCHEMBL6811515 | 0.84 | HTR2C (0.41) | HTR2CALDH1A1LMNAHSD11B1XIAP | |
| SCHEMBL21358968 | 0.80 | LMNA (0.47) | HTR2CALDH1A1LMNAHSD11B1XIAP | |
| SCHEMBL21358964 | 0.80 | LMNA (0.47) | HTR2CALDH1A1LMNAHSD11B1XIAP | |
| SCHEMBL21358963 | 0.80 | LMNA (0.47) | HTR2CALDH1A1LMNAHSD11B1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122001-A1 | Pharmaceutical compounds | ELI LILLY AND COMPANY | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122001-A1 | Pharmaceutical compounds | CYP2D6, LPXN, CYP1B1 | HTR2C 1211/4885ALDH1A1 1563/4885LMNA 1448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.