⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1781286 | 0.82 | ALDH1A1 (0.47) | — | |
| SCHEMBL12640188 | 0.81 | ALDH1A1 (0.53) | — | |
| SCHEMBL1784240 | 0.80 | PAOX (0.48) | — | |
| SCHEMBL28722246 | 0.79 | ALDH1A1 (0.50) | — | |
| SCHEMBL3174218 | 0.79 | — | — | |
| SCHEMBL11690544 | 0.78 | KDM4E (0.52) | — | |
| SCHEMBL5819774 | 0.78 | PAOX (0.52) | — | |
| SCHEMBL8898949 | 0.78 | PAOX (0.52) | — | |
| SCHEMBL1785870 | 0.78 | PAOX (0.52) | — | |
| SCHEMBL26042660 | 0.78 | PAOX (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001010541-A9 | AN APPARATUS AND METHOD FOR IMPROVING AN OSMOSIS PROCESS | BROOKS GERALD L (US) | 2002-09-26 | — | — | WO | claimed |
| EP-1214138-A1 | AN APPARATUS AND METHOD FOR IMPROVING AN OSMOSIS PROCESS | Brooks, Gerald L. (US) | 2002-06-19 | — | — | EP | claimed |
| US-20020008066-A1 | Apparatus and method for improving an osmosis process | EARTH WATERS, INC. | 2002-01-24 | — | — | US | claimed |
| WO-2001010541-A1 | AN APPARATUS AND METHOD FOR IMPROVING AN OSMOSIS PROCESS | EARTH WATERS INC (US) | 2001-02-15 | — | — | WO | claimed |
| US-12037415-B2 | Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient | YUYU PHARMA, INC. (KR) | 2024-07-16 | — | — | US | disclosed |
| US-12030853-B2 | MASP-2 inhibitors and methods of use | OMEROS CORPORATION (US) | 2024-07-09 | — | — | US | disclosed |
| US-20240207412-A1 | DIELS-ALDER CONJUGATION METHODS | REGENERON PHARMACEUTICALS, INC. (US) | 2024-06-27 | — | — | US | disclosed |
| US-20240025903-A1 | Bicyclic Compounds and Uses Thereof for the Treatment of Diseases | ATHIRA PHARMA, INC. (US) | 2024-01-25 | — | — | US | disclosed |
| US-11814391-B2 | Macrocyclic compounds for the treatment of medical disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-20230357199-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | ACHILLION PHARMACEUTICALS, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20230357302-A1 | TRITERPENE SAPONIN VARIANTS, METHODS OF SYNTHESIS AND USE THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER | 2023-11-09 | — | — | US | disclosed |
| US-11807641-B2 | MASP-2 inhibitors and methods of use | OMEROS CORPORATION (US) | 2023-11-07 | — | — | US | disclosed |
| US-7169747-B2 | Bicyclic lactones, perfumery uses thereof, processes for preparing same and intermediates therefor | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2007-01-30 | — | — | US | disclosed |
| US-6252118-B1 | REACTING A KETONE HAVING A BETA HYDROGEN WITH AN OLEFIN CATALYZED BY A TRANSITION METAL CATALYST COMPOUND WITH THE AID OF A 2-AMINOPYRIDINE DERIVATIVE | Jun, Chul Ho (KR) | 2001-06-26 | — | — | US | disclosed |
| EP-0580308-B1 | Working fluid composition for refrigeration machine | KAO CORP (JP) | 2000-11-15 | — | — | EP | disclosed |
| EP-0531715-B1 | Process for producing alcohols and ketones | SUMITOMO CHEMICAL CO (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5426237-A | Oxidation of straight, branched or cyclic alkanes and benzene derivatives in presence of transition metal catalyst and aldehyde | SUMITOMO CHEMICAL CO., LTD. (JP) | 1995-06-20 | — | — | US | disclosed |
| US-5395544-A | Ester-containing working fluid composition for refrigerating machine | KAO CORPORATION (JP) | 1995-03-07 | — | — | US | disclosed |
| EP-0580308-A1 | Working fluid composition for refrigeration machine | KAO CORPORATION (JP) | 1994-01-26 | — | — | EP | disclosed |
| EP-0531715-A1 | Process for producing alcohols and ketones | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-03-17 | — | — | EP | disclosed |