Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PAOX | Q6QHF9 | 5/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1784240 | 0.92 | PAOX (0.48) | ALDH1A1PAOXACHELMNASLC15A2 | |
| SCHEMBL9386368 | 0.90 | PAOX (0.52) | ALDH1A1PAOXACHELMNASLC15A2 | |
| SCHEMBL26042660 | 0.90 | PAOX (0.52) | ALDH1A1PAOXACHELMNASLC15A2 | |
| SCHEMBL8898949 | 0.90 | PAOX (0.52) | ALDH1A1PAOXACHELMNASLC15A2 | |
| SCHEMBL1785870 | 0.90 | PAOX (0.52) | ALDH1A1PAOXACHELMNASLC15A2 | |
| SCHEMBL5819774 | 0.90 | PAOX (0.52) | ALDH1A1PAOXACHELMNASLC15A2 | |
| SCHEMBL681141 | 0.82 | — | — | |
| SCHEMBL8733126 | 0.82 | TSHR (0.50) | ALDH1A1PAOXLMNASLC15A2TDP1 | |
| SCHEMBL11236803 | 0.81 | ALDH1A1 (0.45) | ALDH1A1PAOXACHELMNASLC15A2 | |
| SCHEMBL15457453 | 0.80 | MAPT (0.37) | ALDH1A1TDP1FFAR1CPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043674-B2 | Synthetic cyclic peptides and methods of preparation and use thereof | AUBURN UNIVERSITY (US) | 2024-07-23 | — | — | US | disclosed |
| CN-117534552-A | Method for coproducing diisobutyl ketone from methyl isobutyl ketone | 万华化学集团股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-117500783-A | Perfume compounds | 奇华顿股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117480236-A | Perfume for improving state of agitation and evaluation method | 奇华顿股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-117396591-A | Fragrance and evaluation method for improving happy state | 奇华顿股份有限公司 | 2024-01-12 | — | — | CN | disclosed |
| US-20230357199-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | ACHILLION PHARMACEUTICALS, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20230348450-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS AS MODULATORS OF BIS-PHOSPHOGLYCERATE MUTASE FOR THE TREATMENT OF SICKLE CELL DISEASE | GENZYME CORPORATION | 2023-11-02 | — | — | US | disclosed |
| US-20230348501-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC | 2023-11-02 | — | — | US | disclosed |
| US-11795195-B2 | Antibody-drug conjugates including hemiasterlin derivative | Sumitomo Pharma Co., Ltd. (JP) | 2023-10-24 | — | — | US | disclosed |
| US-11767334-B2 | Heteroaryl inhibitors of PDE4 | Tetra Discovery Partners, LLC (US) | 2023-09-26 | — | — | US | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| CN-102015631-A | Substituted octane (ene) nitriles, process for their synthesis and their use in fragrance making processes | MANE FILS V | 2011-04-13 | — | — | CN | disclosed |
| US-7919523-B2 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS, INC. (US) | 2011-04-05 | — | — | US | disclosed |
| US-20110071142-A1 | IDENTIFICATION AND USE OF SMALL MOLECULES TO MODULATE TRANSCRIPTION FACTOR FUNCTION AND TO TREAT TRANSCRIPTION FACTOR ASSOCIATED DISEASES | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2011-03-24 | — | — | US | disclosed |
| US-7842842-B1 | Hydro-alkoxyl citronellal compounds—synthetic routes, compositions and uses thereof | SAMI LABS LTD. (IN) | 2010-11-30 | — | — | US | disclosed |
| US-20090311401-A1 | Neo-Menthyl Derivatives as Flavor Materials | SYMRISE GMBH & CO. KG (DE) | 2009-12-17 | — | — | US | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
| US-20090042973-A1 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS INCORPORATED | 2009-02-12 | — | — | US | disclosed |
| CN-101360777-A | Prepregs and cured in place solid surfaces prepared therefrom | ASHLAND LICENSING & INTELLECTU (US) | 2009-02-04 | — | — | CN | disclosed |
| US-7442718-B2 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | ALDH1A1 520/4885PAOX 2315/4885ACHE 1079/4885 |
| US-20090042973-A1 | Inhibitors of aspartyl protease | SPINT2, DNPEP, PRSS1 | ALDH1A1 1604/4885PAOX 4599/4885ACHE 887/4885 |
| US-20230348501-A1 | HETEROARYL INHIBITORS OF PDE4 | PDE4A, PDE4B, PDE4C | ALDH1A1 1152/4885PAOX 686/4885ACHE 644/4885 |
| US-20230357199-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | CFD, TFPI, CFH | ALDH1A1 2338/4885PAOX 870/4885ACHE 3216/4885 |
| US-20230348450-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS AS MODULATORS OF BIS-PHOSPHOGLYCERATE MUTASE FOR THE TREATMENT OF SICKLE CELL DISEASE | BPGM, PGAM1, PGM2 | ALDH1A1 326/4885PAOX 135/4885ACHE 3531/4885 |
| US-11795195-B2 | Antibody-drug conjugates including hemiasterlin derivative | HSD3B2, HSD3B1, HSD11B2 | ALDH1A1 1287/4885PAOX 2868/4885ACHE 3754/4885 |
| US-11767334-B2 | Heteroaryl inhibitors of PDE4 | PDE4A, PDE4B, PDE4C | ALDH1A1 1152/4885PAOX 686/4885ACHE 644/4885 |
| US-12043674-B2 | Synthetic cyclic peptides and methods of preparation and use thereof | VIP, PTMS, IAPP | ALDH1A1 4861/4885PAOX 3725/4885ACHE 3813/4885 |
| US-20110071142-A1 | IDENTIFICATION AND USE OF SMALL MOLECULES TO MODULATE TRANSCRIPTION FACTOR FUNCTION AND TO TREAT TRANSCRIPTION FACTOR ASSOCIATED DISEASES | CREBBP, TEAD1, SREBF1 | ALDH1A1 3041/4885PAOX 584/4885ACHE 4848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.