SCHEMBL1784240

SCHEMBL1784240

CC(=O)CCCCC(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 5/20 0.48
ALDH1A1 P00352 3/20 0.45
ACHE P22303 1/20 0.42
LMNA P02545 2/20 0.38
SLC15A2 Q16348 1/20 0.38
TDP1 Q9NUW8 2/20 0.36
GAA P10253 1/20 0.36
FFAR1 O14842 1/20 0.36
CPT2 P23786 1/20 0.36
ACLY P53396 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9386368 0.97 PAOX (0.52) PAOXALDH1A1ACHELMNASLC15A2
SCHEMBL8898949 0.97 PAOX (0.52) PAOXALDH1A1ACHELMNASLC15A2
SCHEMBL26042660 0.97 PAOX (0.52) PAOXALDH1A1ACHELMNASLC15A2
SCHEMBL1785870 0.97 PAOX (0.52) PAOXALDH1A1ACHELMNASLC15A2
SCHEMBL5819774 0.97 PAOX (0.52) PAOXALDH1A1ACHELMNASLC15A2
SCHEMBL1781286 0.92 ALDH1A1 (0.47) PAOXALDH1A1ACHELMNASLC15A2
SCHEMBL8733126 0.89 TSHR (0.50) PAOXALDH1A1LMNASLC15A2TDP1
SCHEMBL15457429 0.81 MAPT (0.41) ALDH1A1LMNATDP1FFAR1CPT2
SCHEMBL681141 0.80
SCHEMBL25705851 0.80 PAOX (0.50) PAOXALDH1A1ACHELMNASLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119925246-A Composition with effects of controlling oil, removing acnes and astringing pores, skin care product and preparation method thereof 湖北省吉美化妆品有限公司 2025-05-06 CN disclosed
US-20240018156-A1 SPIROCYCLIC COMPOUNDS C4 THERAPEUTICS, INC. (US) 2024-01-18 US disclosed
US-20230357180-A1 DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2023-11-09 US disclosed
US-20230226207-A1 Camptothecin Drug Having High-Stability Hydrophilic Connecting Unit And Conjugate Thereof SYSTIMMUNE, INC. 2023-07-20 US disclosed
US-20230159488-A1 APPLICATION OF HETEROCYCLIC COMPOUND CONTAINING AT LEAST TWO SULFUR ATOMS IN PREPARING NANO-VACCINE AND PREPARED NANO-VACCINE Suzhou WEAST Biotechnology Co., Ltd. (CN) 2023-05-25 US disclosed
EP-3562921-B1 LUBRICATING COMPOSITION INCLUDING N-ALKYLATED DIANILINE LUBRIZOL CORP (US) 2022-04-27 EP disclosed
CN-110114448-B Lubricating composition with alkylated naphthylamines 路博润公司 2022-03-04 CN disclosed
US-11162048-B2 Lubricating composition with alkylated naphthylamine THE LUBRIZOL CORPORATION (US) 2021-11-02 US disclosed
EP-3562922-B1 LUBRICATING COMPOSITION WITH ALKYLATED NAPHTHYLAMINE LUBRIZOL CORP (US) 2021-02-03 EP disclosed
EP-3681875-A1 CYCLIC PEPTIDE ANTIBIOTICS H. Hoffnabb-La Roche Ag (CH) 2020-07-22 EP disclosed
US-20130184282-A1 IP RECEPTOR AGONIST HETEROCYCLIC COMPOUNDS NOVARTIS AG (CH) 2013-07-18 US disclosed
US-8476224-B2 Macrocycles and their uses NOVARTIS AG (US) 2013-07-02 US disclosed
US-20130102611-A1 IP RECEPTOR AGONIST HETEROCYCLIC COMPOUNDS NOVARTIS AG (CH) 2013-04-25 US disclosed
US-8324239-B2 Furopyridine compounds and uses thereof NOVARTIS AG (CH) 2012-12-04 US disclosed
US-20120015907-A1 Furopyridine compounds and uses thereof NOVARTIS AG (CH) 2012-01-19 US disclosed
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-05-19 US disclosed
US-7868135-B2 Compositions of lipopeptide antibiotic derivatives and methods of use thereof BIOWEST THERAPEUTICS INC. (CA) 2011-01-11 US disclosed
US-7868135-B2 Compositions of lipopeptide antibiotic derivatives and methods of use thereof BIOWEST THERAPEUTICS INC. (CA) 2011-01-11 US disclosed
WO-2009123355-A2 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-10-08 WO disclosed
US-20090012320-A1 Method for the Production of Olefins from Carbonyl Compounds STUDIENGESELLSCHAFT KOHLE MBH (DE) 2009-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159488-A1 APPLICATION OF HETEROCYCLIC COMPOUND CONTAINING AT LEAST TWO SULFUR ATOMS IN PREPARING NANO-VACCINE AND PREPARED NANO-VACCINE CD4, NFATC1, CTSA PAOX 2639/4885ALDH1A1 4510/4885ACHE 1508/4885
US-20230226207-A1 Camptothecin Drug Having High-Stability Hydrophilic Connecting Unit And Conjugate Thereof SLC7A1, CD44, DCLRE1A PAOX 2834/4885ALDH1A1 2318/4885ACHE 4866/4885
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TRPA1, HRH1, HRH2 PAOX 2315/4885ALDH1A1 520/4885ACHE 1079/4885
US-20240018156-A1 SPIROCYCLIC COMPOUNDS CRBN, XIAP, RBX1 PAOX 685/4885ALDH1A1 1971/4885ACHE 4008/4885
US-20120015907-A1 Furopyridine compounds and uses thereof CYP3A5, QDPR, DPYD PAOX 1319/4885ALDH1A1 178/4885ACHE 469/4885
US-20090012320-A1 Method for the Production of Olefins from Carbonyl Compounds COASY, FASN, PTGES PAOX 603/4885ALDH1A1 165/4885ACHE 2608/4885
US-20230357180-A1 DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION STUB1, MDM2, USP30 PAOX 1625/4885ALDH1A1 3735/4885ACHE 4175/4885
US-20130102611-A1 IP RECEPTOR AGONIST HETEROCYCLIC COMPOUNDS PTGIR, ACVR1, PTGFR PAOX 505/4885ALDH1A1 2869/4885ACHE 4714/4885
US-20130184282-A1 IP RECEPTOR AGONIST HETEROCYCLIC COMPOUNDS PTGIR, GPR68, ACVR1 PAOX 462/4885ALDH1A1 3576/4885ACHE 4344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.