SCHEMBL6811536

SCHEMBL6811536

NC(=O)c1ccc2c(c1)CCCN2CCO

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 4/20 0.61
HDAC6 Q9UBN7 4/20 0.61
HDAC8 Q9BY41 3/20 0.61
HDAC3 O15379 2/20 0.61
HDAC4 P56524 2/20 0.61
HDAC7 Q8WUI4 2/20 0.61
HDAC2 Q92769 2/20 0.61
HDAC11 Q96DB2 2/20 0.61
HDAC9 Q9UKV0 2/20 0.61
HDAC5 Q9UQL6 2/20 0.61
CYP2C19 P33261 1/20 0.61
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 2/20 0.49
HSD17B10 Q99714 2/20 0.49
MEN1 O00255 1/20 0.49
LMNA P02545 1/20 0.49
TP53 P04637 1/20 0.49
GAA P10253 1/20 0.49
MAPT P10636 1/20 0.49
CASP1 P29466 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6990001 0.82 HDAC1 (0.60) HDAC1HDAC6HDAC8HDAC3HDAC4
SCHEMBL6811518 0.81 HDAC1 (0.59) HDAC1HDAC6HDAC8HDAC3HDAC4
SCHEMBL6812251 0.80 HDAC1 (0.53) HDAC1HDAC6HDAC8HDAC3HDAC4
SCHEMBL16061662 0.80 ALDH1A1 (0.55) HDAC1HDAC6HDAC8HDAC3HDAC4
SCHEMBL30197112 0.79 ALDH1A1 (0.53) HDAC1HDAC6HDAC8HDAC3HDAC4
SCHEMBL16558088 0.78 HDAC1 (0.75) HDAC1HDAC6HDAC8HDAC3HDAC4
SCHEMBL11583860 0.78 CHRM2 (0.47) KDM4EALDH1A1HSD17B10MEN1LMNA
SCHEMBL6808175 0.77 MEN1 (0.44) HDAC1HDAC6HDAC8HDAC3HDAC4
SCHEMBL142527 0.76 MAPT (0.48) KDM4EALDH1A1HSD17B10MEN1LMNA
SCHEMBL29100113 0.76 ALDH1A1 (0.62) KDM4EALDH1A1HSD17B10MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112094480-B Resin composition, and prepreg and laminated board manufactured by using same 苏州生益科技有限公司 2023-04-11 CN disclosed
CN-112079763-B Modified maleimide compound, and prepreg and laminated board manufactured by using same 苏州生益科技有限公司 2022-07-05 CN disclosed
CN-112094480-A Resin composition, and prepreg and laminated board manufactured by using same 苏州生益科技有限公司 2020-12-18 CN disclosed
CN-112079763-A Modified maleimide compound, and prepreg and laminated board manufactured by using same 苏州生益科技有限公司 2020-12-15 CN disclosed
CN-112062914-A Resin composition, and prepreg and laminated board manufactured by using same 常熟生益科技有限公司 2020-12-11 CN disclosed
EP-0864592-B1 DIENE RUBBER ZEON CORP (JP) 2004-09-22 EP disclosed
US-20040122001-A1 Pharmaceutical compounds ELI LILLY AND COMPANY 2004-06-24 US disclosed
EP-1345930-A2 PHARMACEUTICAL COMPOUNDS ELI LILLY AND COMPANY (US) 2003-09-24 EP disclosed
WO-2002050067-A2 PHARMACEUTICAL HETEROCYCLIC COMPOUNDS ELI LILLY AND COMPANY (US) 2002-06-27 WO disclosed
US-6211321-B1 CONTAINING A TERTIARY AMINO-CONTAINING VINYL MONOMER AND A HALOGEN CONTAINING VONYL MONOMER NIPPON ZEON CO., LTD. (JP) 2001-04-03 US disclosed
EP-0864592-A1 DIENE RUBBER NIPPON ZEON CO., LTD. (JP) 1998-09-16 EP disclosed
US-5138001-A Optical disc substrates; low birefringence, heat and moisture absorption resistance, high transparency TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1992-08-11 US disclosed
US-4205134-A Carrier for liquid chromatography TOYO SODA MANUFACTURING COMPANY, LTD. (JP) 1980-05-27 US disclosed
US-4128706-A Carrier for liquid chromatography TOYO SODA MANUFACTURING CO., LTD. (JP) 1978-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040122001-A1 Pharmaceutical compounds CYP2D6, LPXN, CYP1B1 HDAC1 3173/4885HDAC6 3196/4885HDAC8 3080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.