Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 3/20 | 0.36 |
| ▸ | PRKCA | P17252 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1173332 | 0.87 | PRKCA (0.47) | LMNANAAAPRKCA | |
| SCHEMBL1173312 | 0.80 | FAAH (0.48) | LMNAHSD17B10PRKCA | |
| SCHEMBL1332682 | 0.77 | TSHR (0.42) | LMNAHSD17B10 | |
| SCHEMBL3142044 | 0.68 | POLB (0.58) | LMNAHAO1 | |
| SCHEMBL28612435 | 0.67 | DGKA (0.59) | HAO1NAAA | |
| SCHEMBL11569429 | 0.67 | FAAH (0.68) | HAO1NAAA | |
| SCHEMBL28609968 | 0.67 | FAAH (0.62) | HAO1NAAA | |
| SCHEMBL6138711 | 0.66 | POLB (0.61) | LMNAHAO1HSD17B10 | |
| SCHEMBL2262562 | 0.66 | HAO1 (0.59) | LMNAHAO1HSD17B10 | |
| SCHEMBL6138719 | 0.66 | POLB (0.61) | LMNAHAO1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064256-B1 | BICYCLO [2.2.1] HEPTANES AND RELATED COMPOUNDS | PFIZER PROD INC (US) | 2004-08-04 | — | — | EP | disclosed |
| EP-1396273-A1 | Bicyclo(2.2.1.)heptanes and related compounds | Pfizer Products Inc. (US) | 2004-03-10 | — | — | EP | disclosed |
| EP-1064256-A1 | BICYCLO [2.2.1] HEPTANES AND RELATED COMPOUNDS | Pfizer Products Inc. (US) | 2001-01-03 | — | — | EP | disclosed |
| US-6136861-A | Bicyclo[2.2.1]heptanes and related compounds | PFIZER INC (US) | 2000-10-24 | — | — | US | disclosed |
| WO-1999047490-A1 | BICYCLO[2.2.1]HEPTANES AND RELATED COMPOUNDS | PFIZER PRODUCTS INC. (US) | 1999-09-23 | — | — | WO | disclosed |