Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4878910 | 0.97 | PIK3CD (0.38) | PIK3CDMPOCYSLTR1MCL1PKM | |
| SCHEMBL6808606 | 0.91 | PIK3CD (0.36) | PIK3CDMPOCYSLTR1PKMTDP1 | |
| SCHEMBL5795016 | 0.89 | PIK3CD (0.36) | PIK3CDMPOCYSLTR1PKMMEN1 | |
| SCHEMBL5793171 | 0.88 | PIK3CD (0.40) | PIK3CDMPOCYSLTR1PKMTDP1 | |
| SCHEMBL4792469 | 0.87 | PIK3CD (0.40) | PIK3CDMPOCYSLTR1PKMTDP1 | |
| SCHEMBL6812741 | 0.87 | PIK3CD (0.36) | PIK3CDMPOCYSLTR1PKMPOLB | |
| SCHEMBL5794401 | 0.87 | PIK3CD (0.36) | PIK3CDPKMTDP1POLBEDNRA | |
| SCHEMBL4790746 | 0.87 | TUBB4A (0.36) | PIK3CDPKMMEN1KMT2AEDNRA | |
| SCHEMBL6811970 | 0.86 | EDNRA (0.45) | PIK3CDMPOCYSLTR1MEN1KMT2A | |
| SCHEMBL4763527 | 0.86 | PIK3CD (0.40) | PIK3CDMPOCYSLTR1PKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248953-A1 | 3-Arylsulfanyl and 3-heteroarylsulfanyl substituted benzo[b]thiophenes as therapeutic agents | GOGLIOTTI ROCCO DEAN (US) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248953-A1 | 3-Arylsulfanyl and 3-heteroarylsulfanyl substituted benzo[b]thiophenes as therapeutic agents | SULT2A1, SULT1A1, SULT1E1 | PIK3CD 3754/4885MPO 3227/4885CYSLTR1 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.