Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4615702 | 0.94 | MMP1 (0.39) | MMP1RORCNPSR1NR1I2KEAP1 | |
| SCHEMBL13898761 | 0.87 | NR3C1 (0.37) | MMP1NR3C1P2RX7MMP13PTGES | |
| SCHEMBL6809611 | 0.85 | MMP1 (0.54) | MMP1FFAR1NR3C1RORCNPSR1 | |
| SCHEMBL6813135 | 0.83 | MMP1 (0.67) | MMP1FFAR1NR3C1RORCNPSR1 | |
| SCHEMBL6813465 | 0.81 | MMP1 (0.55) | MMP1FFAR1NR3C1RORCNPSR1 | |
| SCHEMBL4614633 | 0.78 | MMP1 (0.44) | MMP1RORCNR1I2KEAP1NFE2L2 | |
| SCHEMBL8011711 | 0.78 | CAMK2A (0.37) | MMP1MMP13KEAP1NFE2L2PTGES | |
| SCHEMBL4616560 | 0.76 | MMP1 (0.56) | MMP1RORCNPSR1NR1I2KEAP1 | |
| SCHEMBL4616532 | 0.75 | MMP1 (0.49) | MMP1RORCKEAP1NFE2L2KMT2A | |
| SCHEMBL6872275 | 0.73 | MMP1 (0.43) | MMP1FFAR1NR3C1RORCNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1415984-A1 | Aryloxyarylsulfonylamino hydroxamic acid derivatives | Pfizer Products Inc. (US) | 2004-05-06 | — | — | EP | disclosed |
| EP-1003720-B1 | ARYLOXYARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER PROD INC (US) | 2004-03-31 | — | — | EP | disclosed |
| US-6214872-B1 | ANTIARTHRITIC AND ANTICARCINOGENIC AGENTS | PFIZER INC. | 2001-04-10 | — | — | US | disclosed |
| EP-1003720-A1 | ARYLOXYARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | Pfizer Products Inc. (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007675-A1 | ARYLOXYARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER PRODUCTS INC. (US) | 1999-02-18 | — | — | WO | disclosed |