Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11204869 | 0.78 | — | — | |
| SCHEMBL6817503 | 0.72 | VCAM1 (0.43) | — | |
| SCHEMBL4241910 | 0.67 | MAP2K1 (0.46) | MAP2K1 | |
| SCHEMBL30743052 | 0.67 | MAP2K1 (0.46) | MAP2K1 | |
| SCHEMBL3181238 | 0.66 | ALDH1A1 (0.35) | MAP2K1 | |
| SCHEMBL11759765 | 0.66 | MAPT (0.41) | — | |
| SCHEMBL29229942 | 0.66 | KCNMA1 (0.33) | MAP2K1 | |
| SCHEMBL2966664 | 0.64 | — | — | |
| SCHEMBL6051995 | 0.64 | UPP1 (0.34) | MAP2K1 | |
| SCHEMBL13199488 | 0.64 | KDM4E (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185265-A4 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-02-04 | — | — | EP | disclosed |
| EP-1185265-A1 | IL-8 RECEPTOR ANTAGONISTS | SmithKline Beecham Corporation (US) | 2002-03-13 | — | — | EP | disclosed |
| US-6300325-B1 | HETEROCYCLIC RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM CORPORATION | 2001-10-09 | — | — | US | disclosed |
| WO-2000076501-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-12-21 | — | — | WO | disclosed |
| EP-0991406-A4 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2000-12-13 | — | — | EP | disclosed |
| EP-0991406-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998032439-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-07-30 | — | — | WO | disclosed |