Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.35 |
| ▸ | ITGAL | P20701 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063009 | 0.78 | ITGB2 (0.41) | SMN1; SMN2ITGB2ICAM1ITGAL | |
| SCHEMBL6813240 | 0.75 | KMT2A (0.37) | KMT2ATHRBALOX12ALDH1A1SMN1; SMN2 | |
| SCHEMBL6217553 | 0.74 | ENPP2 (0.34) | ENPP2KMT2AITGB2ICAM1ITGAL | |
| SCHEMBL7064160 | 0.71 | F2R (0.38) | ENPP2KMT2AITGB2ICAM1ITGAL | |
| SCHEMBL6310951 | 0.71 | ITGAL (0.73) | ITGB2ICAM1ITGAL | |
| SCHEMBL6412358 | 0.70 | CYP2C19 (0.66) | HRH3CYP2C19KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6412360 | 0.70 | CYP2C19 (0.66) | HRH3CYP2C19KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5740710 | 0.70 | CYP2C19 (0.66) | HRH3CYP2C19KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9408172 | 0.70 | CYP2C19 (0.66) | HRH3CYP2C19KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL27551808 | 0.68 | CYP2C19 (0.42) | HRH3KCNH2CYP2C19ENPP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | disclosed |