Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813244 | 0.75 | HRH3 (0.38) | KMT2ATHRBALOX12ALDH1A1SMN1; SMN2 | |
| SCHEMBL7064158 | 0.70 | KDM4E (0.36) | KMT2AALDH1A1CA2 | |
| SCHEMBL6310933 | 0.70 | ITGAL (0.51) | SMN1; SMN2 | |
| SCHEMBL3931067 | 0.62 | ACE (0.49) | ACE | |
| SCHEMBL109013 | 0.62 | ACE (0.49) | ACE | |
| SCHEMBL5013232 | 0.62 | ACE (0.49) | ACE | |
| SCHEMBL8552264 | 0.61 | ALDH1A1 (0.57) | KMT2ATHRBALOX12ALDH1A1SMN1; SMN2 | |
| SCHEMBL3148908 | 0.61 | ALDH1A1 (0.57) | KMT2ATHRBALOX12ALDH1A1SMN1; SMN2 | |
| SCHEMBL1681427 | 0.61 | LMNA (0.58) | ACE | |
| SCHEMBL7380987 | 0.61 | LMNA (0.58) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | disclosed |