Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 18/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 18/20 | 0.41 |
| ▸ | ITGAL | P20701 | 18/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065998 | 0.85 | ITGB2 (0.51) | ITGB2ICAM1ITGALHPGDSMN1; SMN2 | |
| SCHEMBL7064160 | 0.81 | F2R (0.38) | ITGB2ICAM1ITGAL | |
| SCHEMBL7065203 | 0.81 | ITGB2 (0.35) | ITGB2ICAM1ITGAL | |
| SCHEMBL6813244 | 0.78 | HRH3 (0.38) | ITGB2ICAM1ITGALSMN1; SMN2 | |
| SCHEMBL27577331 | 0.78 | ITGB2 (0.63) | ITGB2ICAM1ITGAL | |
| SCHEMBL7065799 | 0.76 | GPR183 (0.36) | ITGB2ICAM1ITGAL | |
| SCHEMBL6921387 | 0.76 | L3MBTL1 (0.42) | ITGB2ICAM1ITGALLMNAGAA | |
| SCHEMBL7063010 | 0.73 | RBP4 (0.38) | — | |
| SCHEMBL9653792 | 0.71 | GPR183 (0.60) | LMNAGAAHPGDSMN1; SMN2 | |
| SCHEMBL9653786 | 0.71 | GPR183 (0.60) | LMNAGAAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | claimed |