Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CASP9 | P55211 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6812926 | 0.88 | GAA (0.47) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL7328604 | 0.82 | ESR1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10ESR1 | |
| SCHEMBL2250872 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL2010455 | 0.80 | HMGCR (0.53) | ALDH1A1TSHRHPGDHSD17B10ESR1 | |
| SCHEMBL9080295 | 0.79 | HPGD (0.53) | ALDH1A1KDM4EHPGDHSD17B10ABCB1 | |
| SCHEMBL29843932 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL11683833 | 0.79 | TSHR (0.51) | TSHRKDM4EHSD17B10USP2NPSR1 | |
| SCHEMBL1998630 | 0.78 | ABCB1 (0.67) | ALDH1A1TSHRHPGDABCB1CASP3 | |
| SCHEMBL6812681 | 0.78 | L3MBTL1 (0.50) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL1992123 | 0.78 | PTGDR2 (0.53) | ALDH1A1TSHRKDM4EHPGDESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095932-B1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6538152-B1 | Obesity, hyperglycemia, urinary incontinence, intestinal or biliary calculi hypermotility, pollakiuria and depression treatment | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1095932-A1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2001-05-02 | — | — | EP | disclosed |