Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809817 | 0.88 | GAA (0.47) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL6813799 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL4246167 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL6813642 | 0.79 | ESR1 (0.52) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL29843932 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL4798661 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL6813349 | 0.78 | ABCB1 (0.41) | ALDH1A1TSHRHPGDESR1ABCB1 | |
| SCHEMBL6809927 | 0.78 | L3MBTL1 (0.50) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL2251583 | 0.77 | ALDH1A1 (0.42) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL5178820 | 0.77 | ESR1 (0.44) | ALDH1A1TSHRKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003694-B2 | Crystal of hydroxynorephedrin derivative hydrochloride ¼ hydrate | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2011-08-23 | — | — | US | disclosed |
| US-7763654-B2 | Crystal polymorph of hydroxynorephedrin derivative hydrochloride | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2010-07-27 | — | — | US | disclosed |
| US-20090069421-A1 | CRYSTAL POLYMORPH OF HYDROXYNOREPHEDRIN DERIVATIVE HYDROCHLORIDE | KISSEI PHARMACEUTICAL CO., LTD, (JP) | 2009-03-12 | — | — | US | disclosed |
| US-20090036526-A1 | CRYSTAL OF HYDROXYNOREPHEDRIN DERIVATIVE HYDROCHLORIDE 1/4 HYDRATE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1426355-B1 | CRYSTALS OF HYDROXYNOREPHEDRINE DERIVATIVE | KISSEI PHARMACEUTICAL (JP) | 2008-10-15 | — | — | EP | disclosed |
| EP-1878718-A1 | CRYSTAL OF HYDROXYNOREPHEDRIN DERIVATIVE HYDROCHLORIDE 1/4 HYDRATE | Kissei Pharmaceutical Co., Ltd. (JP) | 2008-01-16 | — | — | EP | disclosed |
| EP-1878719-A1 | CRYSTAL POLYMORPH OF HYDROXYNOREPHEDRIN DERIVATIVE HYDROCHLORIDE | Kissei Pharmaceutical Co., Ltd. (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-7208520-B2 | Crystals of hydroxynorephedrine derivative | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-04-24 | — | — | US | disclosed |
| US-20040242686-A1 | Crystals of hydroxynorephedrine derivative | KISSEI PHARMACEUTICAL CO. LTD. (JP) | 2004-12-02 | — | — | US | disclosed |
| EP-1426355-A1 | CRYSTALS OF HYDROXYNOREPHEDRINE DERIVATIVE | Kissei Pharmaceutical Co., Ltd. (JP) | 2004-06-09 | — | — | EP | disclosed |
| EP-1095932-B1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6538152-B1 | Obesity, hyperglycemia, urinary incontinence, intestinal or biliary calculi hypermotility, pollakiuria and depression treatment | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1095932-A1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2001-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036526-A1 | CRYSTAL OF HYDROXYNOREPHEDRIN DERIVATIVE HYDROCHLORIDE 1/4 HYDRATE | HTR4, HTR1D, HTR3D | ALDH1A1 536/4885TSHR 3708/4885KDM4E 310/4885 |
| US-20090069421-A1 | CRYSTAL POLYMORPH OF HYDROXYNOREPHEDRIN DERIVATIVE HYDROCHLORIDE | HTR3A, HTR3C, HTR3B | ALDH1A1 1336/4885TSHR 3959/4885KDM4E 1310/4885 |
| US-20040242686-A1 | Crystals of hydroxynorephedrine derivative | ADRA2C, ADRB2, ADRA2A | ALDH1A1 363/4885TSHR 1972/4885KDM4E 980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.