Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7525125 | 0.76 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL6813002 | 0.76 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL6813624 | 0.76 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL6812524 | 0.75 | CYP19A1 (0.32) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL7755611 | 0.74 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL7821329 | 0.74 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL27550145 | 0.73 | MAOA (0.38) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7642643 | 0.73 | CYP19A1 (0.31) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL7536192 | 0.72 | CYP19A1 (0.30) | CYP11B1CYP11B2CYP19A1 | |
| Benzene SCHEMBL6817712 | 0.72 | LMNA (0.31) | CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0919574-B1 | Polymerization catalyst, process for the preparation of conjugated diene polymer in the presence thereof and polybutadiene thus prepared | UBE INDUSTRIES (JP) | 2004-02-11 | — | — | EP | disclosed |
| US-6300450-B1 | Conjugated diene compound polymerization catalyst process for the preparation of conjugated diene polymer in the presence thereof and polybutadiene thus prepared | UBE INDUSTRIES, LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0778291-B1 | Catalyst and process for producing conjugated diene polymer | UBE INDUSTRIES (JP) | 2001-03-28 | — | — | EP | disclosed |
| US-6071845-A | OBTAINED BY CONTACTING A COMPOUND OF A TRANSITION METAL OF THE GROUP V OF THE PERIODIC TABLE WITH AN IONIC COMPOUND COMPRISING A NON-COORDINATING ANION AND A CATION AND AN ALUMINOXANE | UBE INDUSTRIES, LTD. (JP) | 2000-06-06 | — | — | US | disclosed |
| EP-0919574-A1 | Polymerization catalyst, process for the preparation of conjugated diene polymer in the presence thereof and polybutadiene thus prepared | Ube Industries, Ltd. (JP) | 1999-06-02 | — | — | EP | disclosed |
| EP-0778291-A1 | Catalyst and process for producing conjugated diene polymer | UBE INDUSTRIES, LTD. (JP) | 1997-06-11 | — | — | EP | disclosed |