Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1064802 | 0.86 | HDAC1 (0.54) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL1065397 | 0.77 | HDAC1 (0.62) | NR1H4MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1064794 | 0.77 | HDAC1 (0.56) | MEN1KMT2AALDH1A1HDAC1HDAC2 | |
| SCHEMBL6814012 | 0.77 | HDAC1 (0.43) | NR1H4MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1061919 | 0.76 | HDAC1 (0.55) | MEN1KMT2AHDAC1HDAC2PDE4D | |
| SCHEMBL1058482 | 0.75 | HDAC1 (0.55) | MEN1KMT2ARAB9AHDAC1HDAC2 | |
| SCHEMBL1064496 | 0.74 | ALDH1A1 (0.51) | NR1H4KMT2AALDH1A1MAPTPDE4D | |
| SCHEMBL1064879 | 0.72 | HDAC1 (0.73) | NR1H4MAPTHDAC1HDAC2NPSR1 | |
| SCHEMBL8349561 | 0.72 | ROCK2 (0.49) | NR1H4KMT2AALDH1A1RAB9APDE4D | |
| SCHEMBL3835550 | 0.71 | HDAC1 (0.44) | HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004005513-A2 | METHODS FOR SPECIFICALLY INHIBITING HISTONE DEACETYLASE-7 AND 8 | METHYLGENE, INC. (CA) | 2004-01-15 | — | — | WO | disclosed |