Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | SI | P14410 | 1/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4169102 | 0.98 | CYP1A2 (0.55) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL250851 | 0.94 | CYP1A2 (0.55) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL380535 | 0.92 | CYP1A2 (0.53) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL11841035 | 0.92 | CYP1A2 (0.53) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL11849466 | 0.92 | CYP1A2 (0.53) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL381525 | 0.92 | CYP1A2 (0.53) | CYP1A2GAAMGAMSIMGAM2 | |
| Hydrochloric Acid SCHEMBL5654547 | 0.90 | CYP1A2 (0.52) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL498980 | 0.86 | — | — | |
| SCHEMBL8636181 | 0.84 | CYP1A2 (0.59) | CYP1A2GAAMGAMSIMGAM2 | |
| Hydrochloric Acid SCHEMBL3295030 | 0.84 | GAA (0.54) | CYP1A2GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098831-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | 嘉兴优博生物技术有限公司 | 2023-06-08 | — | — | WO | disclosed |
| US-20220178921-A1 | 4,4-DISUBSTITUTED CYCLOHEXYL BRIDGED HEPTAMETHINE CYANINE DYES AND USES THEREOF | VISEN MEDICAL, INC. | 2022-06-09 | — | — | US | disclosed |
| US-11193932-B2 | 4,4-disubstituted cyclohexyl bridged heptamethine cyanine dyes and uses thereof | VISEN MEDICAL, INC. (US) | 2021-12-07 | — | — | US | disclosed |
| EP-2953976-B1 | SPECIFIC SITES FOR MODIFYING ANTIBODIES TO MAKE IMMUNOCONJUGATES | NOVARTIS AG (CH) | 2021-03-24 | — | — | EP | disclosed |
| US-20200049709-A1 | 4,4-DISUBSTITUTED CYCLOHEXYL BRIDGED HEPTAMETHINE CYANINE DYES AND USES THEREOF | VISEN MEDICAL, INC. | 2020-02-13 | — | — | US | disclosed |
| US-10473658-B2 | 4,4-disubstituted cyclohexyl bridged heptamethine cyanine dyes and uses thereof | VISEN MEDICAL, INC. (US) | 2019-11-12 | — | — | US | disclosed |
| US-10442930-B2 | Biocompatible N, N-disubstituted sulfonamide-containing fluorescent dye labels | VISEN MEDICAL, INC. (US) | 2019-10-15 | — | — | US | disclosed |
| EP-3489309-A1 | 4,4-DISUBSTITUTED CYCLOHEXYL BRIDGED HEPTAMETHINE CYANINE DYES AND USES THEREOF | Visen Medical, Inc. (US) | 2019-05-29 | — | — | EP | disclosed |
| US-20180164312-A1 | 4,4-DISUBSTITUTED CYCLOHEXYL BRIDGED HEPTAMETHINE CYANINE DYES AND USES THEREOF | VISEN MEDICAL INC. | 2018-06-14 | — | — | US | disclosed |
| US-9897604-B2 | 4,4-disubstituted cyclohexyl bridged heptamethine cyanine dyes and uses thereof | VISEN MEDICAL, INC. (US) | 2018-02-20 | — | — | US | disclosed |
| WO-2007146786-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR RESTORING B-CELL MASS AND FUNCTION | DIAKINE THERAPEUTICS, INC. (US) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007113254-A1 | HIV INHIBITING 5-AMIDO SUBSTITUTED PYRIMIDINES | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2007-10-11 | — | — | WO | disclosed |
| US-20070082896-A1 | Tetrahydroquinoline derivatives and a process for preparing the same | TANABE SEIYAKU CO., LTD. | 2007-04-12 | — | — | US | disclosed |
| US-20070082896-A1 | Tetrahydroquinoline derivatives and a process for preparing the same | TANABE SEIYAKU CO., LTD. | 2007-04-12 | — | — | US | disclosed |
| WO-2007028037-A1 | BIOCOMPATIBLE N, N-DISUBSTITUTED SULFONAMIDE-CONTAINING FLUORESCENT DYE LABELS | VISEN MEDICAL, INC. (US) | 2007-03-08 | — | — | WO | disclosed |
| CN-1922173-A | Indanol Derivatives | SANKYO CO (JP) | 2007-02-28 | — | — | CN | disclosed |
| WO-2006074051-A2 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR RESTORING β-CELL MASS AND FUNCTION | DIAKINE THERAPEUTICS, INC. (US) | 2006-07-13 | — | — | WO | disclosed |
| CN-1053472-C | Oligonucleotides derived from the SOD family | HOFFMANN LA ROCHE (CH) | 2000-06-14 | — | — | CN | disclosed |
| US-5618814-A | Trisubstituted pyrimido [5,4-d] pyrimidines for modulating multi-drug resistance and pharmaceutical compositions containing these compounds | DR. KARL THOMAE GMBH (DE) | 1997-04-08 | — | — | US | disclosed |
| CN-1106405-A | Trisubstituted pyrimido [5,4-d] pyrimidines for modulating | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180164312-A1 | 4,4-DISUBSTITUTED CYCLOHEXYL BRIDGED HEPTAMETHINE CYANINE DYES AND USES THEREOF | CPNE4, LIG4, S100A4 | CYP1A2 2660/4885GAA 4553/4885MGAM 920/4885 |
| US-20070082896-A1 | Tetrahydroquinoline derivatives and a process for preparing the same | CETP, MTTP, NPC1L1 | CYP1A2 1044/4885GAA 3436/4885MGAM 4335/4885 |
| US-20200049709-A1 | 4,4-DISUBSTITUTED CYCLOHEXYL BRIDGED HEPTAMETHINE CYANINE DYES AND USES THEREOF | CPNE4, LIG4, S100A4 | CYP1A2 2660/4885GAA 4553/4885MGAM 920/4885 |
| US-20220178921-A1 | 4,4-DISUBSTITUTED CYCLOHEXYL BRIDGED HEPTAMETHINE CYANINE DYES AND USES THEREOF | CPNE4, LIG4, S100A4 | CYP1A2 2660/4885GAA 4553/4885MGAM 920/4885 |
| US-10473658-B2 | 4,4-disubstituted cyclohexyl bridged heptamethine cyanine dyes and uses thereof | CPNE4, LIG4, S100A4 | CYP1A2 2660/4885GAA 4553/4885MGAM 920/4885 |
| US-11193932-B2 | 4,4-disubstituted cyclohexyl bridged heptamethine cyanine dyes and uses thereof | CPNE4, LIG4, S100A4 | CYP1A2 2660/4885GAA 4553/4885MGAM 920/4885 |
| US-10442930-B2 | Biocompatible N, N-disubstituted sulfonamide-containing fluorescent dye labels | DNPEP, FUT5, NES | CYP1A2 4526/4885GAA 1364/4885MGAM 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.