Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703561 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KDM4ETDP1 | |
| Tetrahydrofuran SCHEMBL2361115 | 0.97 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1 | |
| Tetrahydrofuran SCHEMBL5235661 | 0.94 | ALDH1A1 (0.47) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL8859291 | 0.92 | ALDH1A1 (0.40) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL11713823 | 0.92 | ALDH1A1 (0.40) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL28246276 | 0.90 | ALDH1A1 (0.38) | ALDH1A1KDM4E | |
| Tetrahydrofuran SCHEMBL310535 | 0.89 | ALDH1A1 (0.42) | ALDH1A1TDP1 | |
| Tetrahydrofuran SCHEMBL2336993 | 0.89 | ALDH1A1 (0.42) | ALDH1A1TDP1 | |
| Tetrahydrofuran SCHEMBL28609324 | 0.89 | ALDH1A1 (0.42) | ALDH1A1TDP1 | |
| Dioxane SCHEMBL2949971 | 0.84 | TTR (0.43) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4263539-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) | 2023-10-25 | — | — | EP | disclosed |
| WO-2022129376-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE|TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2022-06-23 | — | — | WO | disclosed |
| WO-2004007467-A1 | NOVEL 3-(3-[AMINOSULFONYLAMINO]-4-CYANO-PHENYL)-6-TRIFLUOROMETHYL-URACILS | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-22 | — | — | WO | disclosed |
| US-5681544-A | Polymer-bonded complexing agents, their complexes and conjugates, processes for their production and pharmaceutical agents containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-10-28 | — | — | US | disclosed |
| US-5420310-A | Anticoagulants, antiulcer, antiatherosclerosis agents formed in multistage reaction | TORAY INDUSTRIES, INC. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0463162-B1 | PREPARATION OF 5,6,7-TRINOR-4,8-INTER-m-PHENYLENE PGI 2 DERIVATIVES | TORAY INDUSTRIES (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5202447-A | Stereospecific | TORAY INDUSTRIES, INC. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0463162-A1 | PREPARATION OF 5,6,7-TRINOR-4,8-INTER-m-PHENYLENE PGI 2 DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1992-01-02 | — | — | EP | disclosed |
| EP-0015079-B1 | HALOGENATING COMPOUNDS AND A PROCESS FOR THEIR PRODUCTION | ELI LILLY AND COMPANY (US) | 1987-09-09 | — | — | EP | disclosed |
| EP-0015079-A1 | Halogenating compounds and a process for their production | ELI LILLY AND COMPANY (US) | 1980-09-03 | — | — | EP | disclosed |
| US-4156723-A | HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1979-05-29 | — | — | US | disclosed |
| US-4123437-A | REACTING A HYDRAZINE WITH AN ALKOXYCARBONYL ISOTHIOCYANATE, CYCLIZATION | CIBA-GEIGY CORPORATION (US) | 1978-10-31 | — | — | US | disclosed |