Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817648 | 0.93 | ABCG2 (0.42) | ABCG2POLBTP53MAPTNPC1 | |
| SCHEMBL6818161 | 0.86 | HIF1A (0.50) | ABCG2POLBTP53MAPTNPC1 | |
| SCHEMBL6817841 | 0.84 | HIF1A (0.50) | ABCG2POLBTP53MAPTNPC1 | |
| SCHEMBL6819716 | 0.82 | PRSS12 (0.47) | POLBALDH1A1MEN1KMT2AHTT | |
| SCHEMBL6818221 | 0.80 | ALB (0.44) | MAPTSMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL6813916 | 0.80 | HIF1A (0.46) | ABCG2POLBTP53MAPTNPC1 | |
| SCHEMBL6818795 | 0.80 | CA12 (0.43) | MAPTMEN1KMT2APRSS12 | |
| SCHEMBL6819722 | 0.79 | KDM4E (0.41) | TP53MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL6817428 | 0.79 | DPP9 (0.40) | POLBMAPTTSHRALDH1A1MEN1 | |
| SCHEMBL6818868 | 0.79 | KMT2A (0.38) | MAPTNPC1RAB9ATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |