Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 2/20 | 0.35 |
| ▸ | PYGM | P11217 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819112 | 0.88 | ABCB1 (0.33) | KDM4EALDH1A1PKMHSD17B10MAPT | |
| SCHEMBL6833638 | 0.85 | KDM4E (0.41) | KDM4EALDH1A1PKMHSD17B10ALB | |
| SCHEMBL6818795 | 0.83 | CA12 (0.43) | KDM4EHSD17B10ALBMAPTCA2 | |
| SCHEMBL6818920 | 0.83 | ALB (0.42) | ALBPYGLPYGMCA2CDK2 | |
| SCHEMBL6818221 | 0.82 | ALB (0.44) | PKMALBTDP1PYGLPYGM | |
| SCHEMBL6818701 | 0.80 | ALB (0.42) | ALBF10 | |
| SCHEMBL6814788 | 0.79 | ABCG2 (0.42) | ALDH1A1MAPTNPC1RAB9ARXFP1 | |
| SCHEMBL6814346 | 0.77 | ALB (0.42) | KDM4EALBABL1RIN1TDP1 | |
| SCHEMBL7129786 | 0.77 | ALB (0.42) | ALDH1A1PKMALBCDK2PRSS12 | |
| SCHEMBL6819716 | 0.76 | PRSS12 (0.47) | ALDH1A1ALBCDK2PRSS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |