Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814011 | 0.89 | ACLY (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6818221 | 0.86 | ALB (0.44) | ALBF10PRSS12MAPTMEN1 | |
| SCHEMBL6817877 | 0.84 | GRIK1 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6830664 | 0.83 | HIF1A (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6819722 | 0.83 | KDM4E (0.41) | CA2ALBF10KDM4EHSD17B10 | |
| SCHEMBL6818701 | 0.82 | ALB (0.42) | ALBF10PPARGMEN1KMT2A | |
| SCHEMBL7129786 | 0.81 | ALB (0.42) | ALBF10PRSS12 | |
| SCHEMBL6814346 | 0.81 | ALB (0.42) | ALBKDM4EAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL6822703 | 0.80 | ALB (0.48) | ALBF10PRSS12 | |
| SCHEMBL6819716 | 0.80 | PRSS12 (0.47) | ALBSERPINE1PRSS12MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |