Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | APEX1 | P27695 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.49 |
| ▸ | RARB | P10826 | 4/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3944688 | 0.85 | TDP1 (0.53) | TP53ESR1POLBAPEX1MAPK1 | |
| SCHEMBL6816018 | 0.83 | TP53 (0.65) | TP53ESR1POLBAPEX1MAPK1 | |
| SCHEMBL15330025 | 0.83 | L3MBTL1 (0.65) | TP53ESR1POLBAPEX1MAPK1 | |
| SCHEMBL11281072 | 0.80 | TP53 (0.61) | TP53ESR1POLBAPEX1MAPK1 | |
| SCHEMBL10446580 | 0.80 | TDP1 (0.48) | TP53ESR1POLBAPEX1MAPK1 | |
| SCHEMBL11525137 | 0.78 | TDP1 (0.46) | TP53ESR1POLBAPEX1MAPK1 | |
| SCHEMBL3945219 | 0.75 | TDP1 (0.55) | TP53ESR1POLBAPEX1MAPK1 | |
| SCHEMBL6815499 | 0.75 | POLB (0.55) | TP53ESR1POLBAPEX1MAPK1 | |
| SCHEMBL30117303 | 0.74 | TDP1 (0.56) | TP53ESR1POLBAPEX1MAPK1 | |
| SCHEMBL898043 | 0.74 | TDP1 (0.42) | TP53ESR1POLBAPEX1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004012656-A2 | THIOPHENE AND FURAN DERIVATIVES AS PROSTAGLANDIN AGONISTS AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2004-02-12 | — | — | WO | claimed |