Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816018 | 0.78 | TP53 (0.65) | POLBTDP1L3MBTL1TP53ESR1 | |
| SCHEMBL6815496 | 0.75 | PTGER4 (0.61) | POLBTDP1L3MBTL1HRH3MRGPRX4 | |
| SCHEMBL15330025 | 0.75 | L3MBTL1 (0.65) | POLBTDP1L3MBTL1TP53ESR1 | |
| SCHEMBL6810690 | 0.73 | POLB (0.63) | POLBTDP1L3MBTL1APEX1MAPK1 | |
| SCHEMBL5274797 | 0.72 | MEN1 (0.70) | POLBHRH3KMT2AMEN1NPC1 | |
| SCHEMBL5326805 | 0.70 | MEN1 (0.67) | POLBHRH3KMT2AMEN1NPC1 | |
| SCHEMBL30117303 | 0.70 | TDP1 (0.56) | POLBTDP1L3MBTL1TP53ESR1 | |
| SCHEMBL5249481 | 0.69 | HRH3 (0.60) | L3MBTL1HRH3MRGPRX4KMT2ARAB9A | |
| SCHEMBL11720322 | 0.69 | HRH3 (0.57) | POLBHRH3FFAR4KMT2AMEN1 | |
| SCHEMBL8062861 | 0.68 | ACMSD (0.55) | POLBHRH3MRGPRX4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004012656-A2 | THIOPHENE AND FURAN DERIVATIVES AS PROSTAGLANDIN AGONISTS AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2004-02-12 | — | — | WO | disclosed |