Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | PPARD | Q03181 | 4/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817053 | 0.93 | PPARD (0.43) | PPARAPPARDPTGER1ALDH1A1TP53 | |
| SCHEMBL6813055 | 0.89 | ALDH1A1 (0.44) | PPARAPPARDPTGER1ALDH1A1TP53 | |
| SCHEMBL6816682 | 0.89 | LMNA (0.53) | ALDH1A1MAPTLMNACA12CA1 | |
| SCHEMBL6817386 | 0.88 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNACA12CA1 | |
| SCHEMBL6816474 | 0.88 | GAA (0.52) | ALDH1A1TP53LMNAGAA | |
| SCHEMBL6544322 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNACA12CA1 | |
| SCHEMBL4367196 | 0.82 | TMEM97 (0.55) | PPARAPPARDACHE | |
| SCHEMBL4367223 | 0.82 | TMEM97 (0.55) | PPARAPPARDACHE | |
| SCHEMBL4367191 | 0.82 | TMEM97 (0.55) | PPARAPPARDACHE | |
| SCHEMBL6816190 | 0.82 | LMNA (0.52) | ALDH1A1MAPTLMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140799-B1 | NOVEL PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-02 | — | — | EP | claimed |
| US-6469005-B1 | CONTROLLING AND PROTECTING AGAINST PHYTOPATHOGENIC MICROORGANISMS | SYNGENTA PARTICIPATIONS AG (CH) | 2002-10-22 | — | — | US | claimed |
| EP-1140799-A1 | NOVEL PROPARGYLETHER DERIVATIVES | Syngenta Participations AG (CH) | 2001-10-10 | — | — | EP | claimed |
| WO-2000041998-A1 | NOVEL PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-07-20 | — | — | WO | claimed |
| EP-1140799-B1 | NOVEL PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-02 | — | — | EP | disclosed |
| US-6469005-B1 | CONTROLLING AND PROTECTING AGAINST PHYTOPATHOGENIC MICROORGANISMS | SYNGENTA PARTICIPATIONS AG (CH) | 2002-10-22 | — | — | US | disclosed |
| EP-1140799-A1 | NOVEL PROPARGYLETHER DERIVATIVES | Syngenta Participations AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000041998-A1 | NOVEL PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-07-20 | — | — | WO | disclosed |