Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4367196 | 1.00 | TMEM97 (0.55) | TMEM97DUSP3MTNR1AMTNR1BALOX5 | |
| SCHEMBL4367223 | 1.00 | TMEM97 (0.55) | TMEM97DUSP3MTNR1AMTNR1BALOX5 | |
| SCHEMBL4363914 | 0.88 | MTNR1A (0.52) | MTNR1AMTNR1BALOX5OR51E2NOX4 | |
| SCHEMBL4376901 | 0.88 | MTNR1A (0.52) | MTNR1AMTNR1BALOX5OR51E2NOX4 | |
| SCHEMBL4363908 | 0.88 | MTNR1A (0.52) | MTNR1AMTNR1BALOX5OR51E2NOX4 | |
| SCHEMBL4368024 | 0.87 | MTNR1A (0.53) | MTNR1AMTNR1BALOX5OR51E2NOX4 | |
| SCHEMBL4367213 | 0.87 | LMNA (0.56) | MTNR1AMTNR1BALOX5OR51E2NOX4 | |
| SCHEMBL4368020 | 0.87 | MTNR1A (0.53) | MTNR1AMTNR1BALOX5OR51E2NOX4 | |
| SCHEMBL4367219 | 0.87 | LMNA (0.56) | MTNR1AMTNR1BALOX5OR51E2NOX4 | |
| SCHEMBL4372465 | 0.87 | LMNA (0.56) | MTNR1AMTNR1BALOX5OR51E2NOX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521579-B2 | Process for the preparation of alpha hydroxycarboxylic acid amides | SYNGENTA CROP PROTECTION, INC. (US) | 2009-04-21 | — | — | US | disclosed |
| EP-1526128-B1 | Process the preparation of alpha-hydroxycarboxylic acid amides | SYNGENTA PARTICIPATIONS AG (CH) | 2007-01-03 | — | — | EP | disclosed |
| EP-1444195-B1 | PROCESS FOR THE PREPARATION OF ALPHA-HYDROXYCARBOXYLIC ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-08-10 | — | — | EP | disclosed |
| EP-1526128-A2 | Process the preparation of alpha-hydroxycarboxylic acid amides | Syngenta Participations AG (CH) | 2005-04-27 | — | — | EP | disclosed |
| US-20050014950-A1 | Process for the preparation of alpha hydroxycarboxylic acid amides | SYNGENTA CROP PROTECTION, INC. | 2005-01-20 | — | — | US | disclosed |
| EP-1444195-A2 | PROCESS FOR THE PREPARATION OF ALPHA-HYDROXYCARBOXYLIC ACID AMIDES | Syngenta Participations AG (CH) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003042166-A2 | PROCESS FOR PREPARATION OF α-HYDROXYCARBOXYLIC ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014950-A1 | Process for the preparation of alpha hydroxycarboxylic acid amides | HCAR1, HCAR3, HCAR2 | TMEM97 599/4885DUSP3 4161/4885MTNR1A 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.