SCHEMBL6815862

SCHEMBL6815862

C#CCCCCCCNC(=O)C(F)(F)F

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.70
KMT2A Q03164 1/20 0.70
ALDH1A1 P00352 4/20 0.67
SMN1; SMN2 Q16637 4/20 0.67
POLB P06746 1/20 0.67
EPHX1 P07099 1/20 0.59
CA3 P07451 2/20 0.58
CA5A P35218 2/20 0.58
CA5B Q9Y2D0 2/20 0.58
CA14 Q9ULX7 2/20 0.58
CA2 P00918 2/20 0.58
CA12 O43570 1/20 0.58
CA4 P22748 1/20 0.58
CA6 P23280 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
MAPT P10636 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9369234 1.00 MEN1 (0.70) MEN1KMT2AALDH1A1SMN1; SMN2POLB
SCHEMBL6816081 0.98 ALDH1A1 (0.69) MEN1KMT2AALDH1A1SMN1; SMN2POLB
SCHEMBL6819313 0.92 ALDH1A1 (0.65) MEN1KMT2AALDH1A1SMN1; SMN2POLB
SCHEMBL25756505 0.86 CA3 (0.70) MEN1KMT2AALDH1A1SMN1; SMN2POLB
SCHEMBL13787269 0.84 ALDH1A1 (0.58) MEN1KMT2AALDH1A1SMN1; SMN2POLB
SCHEMBL29982917 0.84 MEN1 (1.00) MEN1KMT2AALDH1A1SMN1; SMN2POLB
SCHEMBL27889238 0.82 ALDH1A1 (1.00) MEN1KMT2AALDH1A1SMN1; SMN2POLB
SCHEMBL2001127 0.78 MEN1 (0.59) MEN1KMT2AALDH1A1SMN1; SMN2POLB
SCHEMBL570465 0.78 CA3 (0.91) MEN1KMT2AALDH1A1SMN1; SMN2POLB
SCHEMBL3215133 0.76 MEN1 (0.83) MEN1KMT2AALDH1A1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0978569-B1 METHOD OF DNA SEQUENCING RIKAGAKU KENKYUSHO (JP) 2004-09-22 EP disclosed
US-6365350-B1 REACTING RIBONUCLEOTIDE 5'-TRIPHOSPHATES AND 3'-DEOXY NUCLEOTIDE TRIPHOSPHATES WITH RNA POLYMERASE AND DNA FRAGMENT CONTAINING A PROMOTER SEQUENCE FOR THE POLYMERASE, THEN SEPARATING THE TRANSCRIPTION PRODUCT AND SEQUENCING IT THE INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH (JP) 2002-04-02 US disclosed
US-6265569-B1 HAS ALKYL LINKER INCLUDING DOUBLE OR TRIPLE BOND WHICH ATTACHES FLUORESCENT MOLECULE TO NUCLEOTIDE; FOR TERMINATORS IN DNA SEQUENCING USING RNA POLYMERASES THE INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH (JP) 2001-07-24 US disclosed
EP-1046648-A1 3'-DEOXYRIBONUCLEOTIDE DERIVATIVES THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH (JP) 2000-10-25 EP disclosed
EP-0978569-A1 METHOD OF DNA SEQUENCING THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH (JP) 2000-02-09 EP disclosed