Tetrahydrofuran

Tetrahydrofuran

SCHEMBL6816688

C1CCOC1.[Ar]

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL378197 0.94 ALDH1A1 (1.00)
Tetrahydrofuran SCHEMBL479 0.94
SCHEMBL30466481 0.94 ALDH1A1 (1.00)
Tetrahydrofuran SCHEMBL1982618 0.94
SCHEMBL3455441 0.94 ALDH1A1 (1.00)
Tetrahydrofuran SCHEMBL6298732 0.94
SCHEMBL30432886 0.94 ALDH1A1 (1.00)
SCHEMBL9576477 0.94 ALDH1A1 (1.00)
Tetrahydrofuran SCHEMBL130914 0.94
Tetrahydrofuran SCHEMBL6364293 0.94 ALDH1A1 (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110198930-A Pyrimidine derivatives 第一三共株式会社 2019-09-03 CN disclosed
CN-109678796-A PD-1/PD-L1 micromolecular inhibitor and its preparation method and application 上海长森药业有限公司 2019-04-26 CN disclosed
CN-104592464-B A kind of organic inorganic hybridization block copolymer and its synthetic method containing POSS and amphion structure 厦门大学 2017-07-25 CN disclosed
CN-104768944-A 2-pyridone compound TAISHO PHARMACEUTICAL CO LTD 2015-07-08 CN disclosed
CN-102010286-A 9-(9-methyl-9H-fluorene-yl)anthracene and synthetic method thereof UNIV SHANGHAI 2011-04-13 CN disclosed
CN-101772477-A supported iridium catalysts UNIV NORTH CAROLINA 2010-07-07 CN disclosed
CN-1230425-C Optical active compound used as intermediate in preparing optical activity 2-imidazoline-5-thionone derivatives RHONE POULENC AGROCHIMIE (FR) 2005-12-07 CN disclosed
CN-1229336-C Photoactive compound used as intermediate for preparing photoactive 2-imidazoline-5-ketone or 2-imdazoline-5-thio-ketone derivative RHONE POULENC AGROCHIMIE (FR) 2005-11-30 CN disclosed
EP-1137632-B1 THIOUREA INHIBITORS OF HERPES VIRUSES WYETH CORP (US) 2004-07-28 EP disclosed
CN-1511832-A Optical active compound used as intermediate in preparing optical activity 2-imidazoline-5-thionone derivatives ����-���ʿ�ũҵ��ѧ��˾ 2004-07-14 CN disclosed
WO-2000034269-A1 THIOUREA INHIBITORS OF HERPES VIRUSES AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 WO disclosed
WO-2000034261-A2 HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A SUBSTITUTED PHENYLENEDIAMINE GROUP AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 WO disclosed
WO-2000034260-A2 ALPHA-METHYLBENZYL-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A PHENYLENEDIAMINE GROUP AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 WO disclosed
WO-2000034268-A1 THIOUREA INHIBITORS OF HERPES VIRUSES AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 WO disclosed
WO-2000034238-A1 THIOUREA INHIBITORS OF HERPES VIRUSES AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 WO disclosed
WO-2000034237-A2 ACETAMIDE AND SUBSTITUTED ACETAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 WO disclosed
WO-2000034258-A2 HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 WO disclosed
EP-1007506-A2 COMPOSITIONS AND METHODS FOR REVERSIBLY INCREASING PERMEABILITY OF BIOMEMBRANES D-PHARM, LTD. (IL) 2000-06-14 EP disclosed
WO-1999002120-A2 COMPOSITIONS AND METHODS FOR REVERSIBLY INCREASING PERMEABILITY OF BIOMEMBRANES D-PHARM LTD. (IL) 1999-01-21 WO disclosed
WO-1999002485-A1 BRANCHED CHAIN FATTY ACIDS, THEIR DERIVATIVES AND USE IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS D-PHARM LTD. (IL) 1999-01-21 WO disclosed