SCHEMBL681776

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL131273	0.97	PDE4A (0.50)	PDE4BPDE4APDE4DPDE4CNPY1R
	SCHEMBL127226	0.93	SLC6A4 (0.48)	PDE4BPDE4APDE4DPDE4CSLC6A4
	SCHEMBL1157303	0.81	PDE4D (0.53)	PDE4BPDE4APDE4DPDE4C
	SCHEMBL6876750	0.81	PDE4D (0.56)	PDE4BPDE4APDE4DPDE4C
	SCHEMBL682486	0.80	MAPK1 (0.43)	PDE4BPDE4APDE4DPDE4CSLC6A4
	SCHEMBL129356	0.80	PDE4A (0.59)	PDE4BPDE4APDE4DPDE4CNPY1R
	SCHEMBL5704271	0.79	PDE4A (0.57)	PDE4BPDE4APDE4DPDE4CNPY1R
	SCHEMBL20063995	0.79	PDE4D (0.51)	PDE4BPDE4APDE4DPDE4C
	SCHEMBL5880750	0.78	NPY1R (0.50)	PDE4BPDE4APDE4DPDE4CNPY1R
	SCHEMBL20064317	0.77	PDE4D (0.53)	PDE4BPDE4APDE4DPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.