Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817683 | 0.91 | HIF1A (0.44) | HIF1ATSHRTP53HTTMEN1 | |
| SCHEMBL6817347 | 0.90 | ALDH1A1 (0.40) | HIF1ATP53HTTALDH1A1HSD17B10 | |
| SCHEMBL6818399 | 0.90 | HIF1A (0.46) | HIF1ATSHRTP53HTTMEN1 | |
| SCHEMBL6818297 | 0.89 | HIF1A (0.45) | HIF1ATSHRTP53HTTMEN1 | |
| SCHEMBL6818765 | 0.89 | ALB (0.37) | HIF1AHTTKMT2AALDH1A1HSD17B10 | |
| SCHEMBL6818178 | 0.89 | HIF1A (0.43) | HIF1ATSHRTP53HTTMEN1 | |
| SCHEMBL6813726 | 0.88 | AGPAT2 (0.37) | HIF1ATP53ALDH1A1NPC1RAB9A | |
| SCHEMBL6819127 | 0.88 | ALDH1A1 (0.39) | HIF1ATP53HTTALDH1A1HSD17B10 | |
| SCHEMBL6817520 | 0.87 | HIF1A (0.43) | HIF1ATSHRTP53HTTMEN1 | |
| SCHEMBL6819666 | 0.87 | ALDH1A1 (0.38) | HIF1ATP53HTTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |