Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548559 | 0.84 | TSHR (0.57) | TSHRLMNAKDM4EHSD17B10MGAM | |
| SCHEMBL6463788 | 0.81 | TSHR (0.50) | TSHRLMNAKDM4EHSD17B10MGAM | |
| SCHEMBL22092864 | 0.80 | TSHR (0.52) | TSHRLMNAKDM4EHSD17B10MGAM | |
| SCHEMBL5840370 | 0.79 | TSHR (0.43) | TSHRLMNAKDM4EHSD17B10MGAM | |
| SCHEMBL7648165 | 0.79 | TSHR (0.48) | TSHRLMNAKDM4EHSD17B10MGAM | |
| SCHEMBL3149738 | 0.77 | — | — | |
| SCHEMBL28630314 | 0.76 | TSHR (0.40) | TSHRLMNAKDM4EHSD17B10MGAM | |
| SCHEMBL1335833 | 0.75 | TSHR (0.56) | TSHRLMNAKDM4EHSD17B10MGAM | |
| SCHEMBL2449256 | 0.75 | ALDH1A1 (0.37) | TSHRLMNAKDM4EHSD17B10GAA | |
| SCHEMBL260944 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38551-E1 | ADMINISTERING N-BENZYL-2- ACETAMIDO PROPIONAMIDE DERIVATIVES IN THE R CONFIGURATION, SUCH AS LACOSAMIDE | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2004-07-06 | — | — | US | disclosed |
| EP-1038522-B1 | Anticonvulsant enantiomeric amino acid derivatives | RES CORP TECHNOLOGIES INC (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-0888289-B1 | ANTICONVULSANT ENANTIOMERIC AMINO ACID DERIVATIVES | RES CORP TECHNOLOGIES INC (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-1038522-A2 | Anticonvulsant enantiomeric amino acid derivatives | Research Corporation Technologies, Inc (US) | 2000-09-27 | — | — | EP | disclosed |
| US-5773475-A | DIPEPTIDES FOR CENTRAL NERVOUS SYSTEM DISORDERS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1998-06-30 | — | — | US | disclosed |