Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GNRHR | P30968 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6476432 | 0.97 | ALDH1A1 (0.47) | ALDH1A1LMNAKDM4EHPGDGAA | |
| SCHEMBL6487093 | 0.90 | NR1H4 (0.46) | ALDH1A1KDM4EHPGDKMT2ACYP2C19 | |
| SCHEMBL6485436 | 0.88 | CNR2 (0.40) | ALDH1A1LMNAGAATSHRKMT2A | |
| SCHEMBL6475923 | 0.79 | MAPT (0.46) | ALDH1A1LMNAKDM4EHPGDGAA | |
| SCHEMBL6288785 | 0.74 | LMNA (0.47) | ALDH1A1LMNAKDM4EHPGDKMT2A | |
| SCHEMBL6486582 | 0.71 | MAPT (0.46) | ALDH1A1LMNATRPA1KMT2AL3MBTL1 | |
| SCHEMBL6483747 | 0.71 | NR1H4 (0.44) | ALDH1A1LMNAKDM4EHPGDKMT2A | |
| SCHEMBL6483805 | 0.70 | KLK1 (0.47) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL6488185 | 0.70 | TRPA1 (0.53) | ALDH1A1LMNAHPGDTRPA1MAPT | |
| SCHEMBL6919813 | 0.70 | PTGER4 (0.45) | LMNATRPA1MAPTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014908-A1 | HETEROBICYLCIC METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |