Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.31 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862572 | 1.00 | NFKB1 (0.37) | NFKB1NFKB2RELAALDH1A1SOAT1 | |
| SCHEMBL7862444 | 0.88 | ASGR1 (0.33) | NFKB1NFKB2RELAALDH1A1MAPK1 | |
| SCHEMBL6818332 | 0.88 | ASGR1 (0.33) | NFKB1NFKB2RELAALDH1A1MAPK1 | |
| SCHEMBL7862552 | 0.85 | HPGD (0.39) | ALDH1A1MAPK1LMNACYP2C19ASGR1 | |
| SCHEMBL6821109 | 0.83 | CYP1A2 (0.31) | HSD17B10CYP2C19CYP1A2 | |
| SCHEMBL6821237 | 0.83 | CYP1A2 (0.31) | HSD17B10CYP2C19CYP1A2 | |
| SCHEMBL6821414 | 0.80 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL31739235 | 0.80 | ALDH1A1 (0.41) | NFKB1NFKB2RELAALDH1A1SOAT1 | |
| SCHEMBL6917661 | 0.78 | NFKB1 (0.39) | NFKB1NFKB2RELAALDH1A1HSD17B10 | |
| SCHEMBL6836199 | 0.78 | NFKB1 (0.39) | NFKB1NFKB2RELAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095160-B1 | METHOD FOR PRODUCING (1R,4S)-2-AZABICYCLO 2.2.1 HEPT-5-EN-3-ON DERIVATIVES. | LONZA AG (CH) | 2004-01-28 | — | — | EP | claimed |
| EP-1095160-B1 | METHOD FOR PRODUCING (1R,4S)-2-AZABICYCLO 2.2.1 HEPT-5-EN-3-ON DERIVATIVES. | LONZA AG (CH) | 2004-01-28 | — | — | EP | disclosed |
| EP-1095160-A1 | METHOD FOR PRODUCING (1R,4S)-2-AZABICYCLO 2.2.1 HEPT-5-EN-3-ON DERIVATIVES. | Lonza AG (CH) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000003032-A1 | METHOD FOR PRODUCING (1R,4S)-2-AZABICYLCO[2.2.1]HEPT-5-EN-3-ON DERIVATIVES | LONZA AG (CH) | 2000-01-20 | — | — | WO | disclosed |