Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASGR1 | P07306 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818332 | 1.00 | ASGR1 (0.33) | ASGR1KDM4EGLAALDH1A1ESR1 | |
| SCHEMBL6818575 | 0.92 | HPGD (0.39) | ASGR1ALDH1A1ESR1TSHRSMN1; SMN2 | |
| SCHEMBL7862552 | 0.92 | HPGD (0.39) | ASGR1ALDH1A1ESR1TSHRSMN1; SMN2 | |
| SCHEMBL7862572 | 0.88 | NFKB1 (0.37) | ASGR1ALDH1A1RAB9ANFKB1NFKB2 | |
| SCHEMBL6818528 | 0.88 | NFKB1 (0.37) | ASGR1ALDH1A1RAB9ANFKB1NFKB2 | |
| SCHEMBL6821109 | 0.81 | CYP1A2 (0.31) | SMN1; SMN2 | |
| SCHEMBL6821237 | 0.81 | CYP1A2 (0.31) | SMN1; SMN2 | |
| SCHEMBL6841531 | 0.79 | ALDH1A1 (0.35) | ASGR1KDM4EGLAALDH1A1ESR1 | |
| SCHEMBL6841385 | 0.79 | ALDH1A1 (0.35) | ASGR1KDM4EGLAALDH1A1ESR1 | |
| SCHEMBL6821414 | 0.78 | SMN1; SMN2 (0.34) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095160-A1 | METHOD FOR PRODUCING (1R,4S)-2-AZABICYCLO 2.2.1 HEPT-5-EN-3-ON DERIVATIVES. | Lonza AG (CH) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000003032-A1 | METHOD FOR PRODUCING (1R,4S)-2-AZABICYLCO[2.2.1]HEPT-5-EN-3-ON DERIVATIVES | LONZA AG (CH) | 2000-01-20 | — | — | WO | disclosed |