Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818619 | 0.88 | GRM5 (0.44) | GRM5BLM | |
| SCHEMBL6583010 | 0.82 | KDM4E (0.48) | KDM4EBLMALOX15 | |
| SCHEMBL6583004 | 0.82 | KDM4E (0.48) | KDM4EBLMALOX15 | |
| SCHEMBL6818776 | 0.81 | CHRNB4 (0.59) | KDM4EBLMALOX15 | |
| SCHEMBL17753546 | 0.79 | CHRNB2 (0.64) | KDM4EBLMALOX15 | |
| Benzoic Acid SCHEMBL31344150 | 0.77 | KDM4E (0.53) | KDM4EBLMALOX15 | |
| Benzoic Acid SCHEMBL28883890 | 0.77 | KDM4E (0.53) | KDM4EBLMALOX15 | |
| Benzoic Acid SCHEMBL27199890 | 0.77 | KDM4E (0.53) | KDM4EBLMALOX15 | |
| SCHEMBL6814485 | 0.76 | HRH3 (0.46) | KDM4EBLMALOX15 | |
| SCHEMBL6582951 | 0.75 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1079860-B1 | NICOTINE IMMUNOGEN | INDEPENDENT PHARMACEUTICA AB (SE) | 2004-10-27 | — | — | EP | disclosed |
| US-6656469-B1 | Treatment of nicotine dependence from tobacco products | INDEPENDENT PHARMACEUTICA AB (SE) | 2003-12-02 | — | — | US | disclosed |
| EP-1079860-A1 | NICOTINE IMMUNOGEN | Independent pharmaceutica AB (SE) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999061054-A1 | NICOTINE IMMUNOGEN | INDEPENDENT PHARMACEUTICA AB (SE) | 1999-12-02 | — | — | WO | disclosed |