Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 14/20 | 0.69 |
| ▸ | ADRA2A | P08913 | 13/20 | 0.69 |
| ▸ | ADRA2B | P18089 | 11/20 | 0.69 |
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821569 | 0.86 | ADRA2C (0.82) | ADRA2CADRA2AADRA2BKDM1AGAA | |
| SCHEMBL6919721 | 0.85 | ADRA2C (0.92) | ADRA2CADRA2AADRA2BKDM1AGAA | |
| SCHEMBL6822526 | 0.82 | ADRA2C (1.00) | ADRA2CADRA2AADRA2BKDM1AGAA | |
| SCHEMBL6920151 | 0.81 | ADRA2C (0.79) | ADRA2CADRA2AADRA2B | |
| SCHEMBL7123693 | 0.70 | ADRA2A (1.00) | ADRA2CADRA2AADRA2BKDM1ATDP1 | |
| SCHEMBL6821566 | 0.69 | ADRA2C (0.84) | ADRA2CADRA2AADRA2BKDM1ATDP1 | |
| SCHEMBL6922102 | 0.67 | ADRA2A (0.92) | ADRA2CADRA2AADRA2BKDM1ATDP1 | |
| SCHEMBL6824787 | 0.66 | ADRA2A (0.84) | ADRA2CADRA2AADRA2B | |
| SCHEMBL7159038 | 0.66 | ADRA2C (0.70) | ADRA2CADRA2AADRA2BKDM1ATDP1 | |
| SCHEMBL7128192 | 0.65 | KDM4E (0.68) | ADRA2CADRA2AADRA2BMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067513-A1 | ANTAGONISTS FOR ALPHA-2 ADRENOCEPTORS | OY JUVANTIA PHARMA LTD (FI) | 2004-08-12 | — | — | WO | claimed |
| WO-2004067513-A1 | ANTAGONISTS FOR ALPHA-2 ADRENOCEPTORS | OY JUVANTIA PHARMA LTD (FI) | 2004-08-12 | — | — | WO | disclosed |