Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 10/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818666 | 0.93 | TRPA1 (0.44) | TRPA1RXFP1LMNAPOLBMAPT | |
| SCHEMBL6486746 | 0.82 | NR1H4 (0.45) | LMNAPOLBMAPTALDH1A1HPGD | |
| SCHEMBL6488185 | 0.82 | TRPA1 (0.53) | TRPA1RXFP1LMNAPOLBMAPT | |
| SCHEMBL6476120 | 0.75 | TRPA1 (0.54) | TRPA1RXFP1LMNAPOLBMAPT | |
| SCHEMBL6817764 | 0.72 | MAPT (0.37) | RXFP1LMNAPOLBMAPT | |
| SCHEMBL6814150 | 0.70 | TRPA1 (0.51) | TRPA1SMN1; SMN2MAPT | |
| SCHEMBL6483921 | 0.66 | MAPT (0.45) | RXFP1LMNAPOLBMAPTALDH1A1 | |
| SCHEMBL6483805 | 0.65 | KLK1 (0.47) | RXFP1SMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL6817760 | 0.65 | MAPT (0.38) | RXFP1LMNAPOLBMAPT | |
| SCHEMBL6488181 | 0.65 | NR1H4 (0.44) | LMNAMAPTALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014908-A1 | HETEROBICYLCIC METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |