Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 7/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814152 | 0.83 | MEN1 (0.37) | TRPA1MAPK14 | |
| SCHEMBL6476120 | 0.81 | TRPA1 (0.54) | TRPA1MAPT | |
| SCHEMBL6488185 | 0.81 | TRPA1 (0.53) | TRPA1MAPT | |
| SCHEMBL6484094 | 0.81 | LMNA (0.42) | TRPA1MAPTCYP3A4CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL5957637 | 0.77 | TRPA1 (0.81) | TRPA1L3MBTL1MAPT | |
| SCHEMBL6486582 | 0.75 | MAPT (0.46) | TRPA1L3MBTL1MAPTSMN1; SMN2CHRM4 | |
| SCHEMBL6818666 | 0.72 | TRPA1 (0.44) | TRPA1MAPT | |
| SCHEMBL6919813 | 0.71 | PTGER4 (0.45) | TRPA1MAPTSMN1; SMN2CHRM4 | |
| SCHEMBL6476432 | 0.70 | ALDH1A1 (0.47) | TRPA1L3MBTL1MAPTCYP2C19SMN1; SMN2 | |
| SCHEMBL5957688 | 0.70 | TRPA1 (0.69) | TRPA1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014908-A1 | HETEROBICYLCIC METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | claimed |