Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | CRHBP | P24387 | 1/20 | 0.61 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814899 | 0.89 | MAPT (0.56) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6811089 | 0.88 | LMNA (0.59) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6815597 | 0.85 | MAPT (0.61) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6814650 | 0.84 | ALDH1A1 (0.61) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6816140 | 0.84 | MAPT (0.63) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6814993 | 0.83 | MEN1 (0.58) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6819815 | 0.83 | MAPT (0.50) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6819280 | 0.82 | LMNA (0.52) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6814574 | 0.81 | ALDH1A1 (0.60) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6815402 | 0.81 | MEN1 (0.51) | MAPTMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137632-B1 | THIOUREA INHIBITORS OF HERPES VIRUSES | WYETH CORP (US) | 2004-07-28 | — | — | EP | disclosed |
| EP-1137645-B1 | ALPHA-METHYLBENZYL-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A PHENYLENEDIAMINE GROUP | WYETH CORP (US) | 2004-05-26 | — | — | EP | disclosed |
| US-6426355-B1 | VIRICIDES; PREVENTION PRODUCTION | AMERICAN HOME PRODUCTS | 2002-07-30 | — | — | US | disclosed |