Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.44 |
| ▸ | CTSK | P43235 | 7/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22636135 | 1.00 | CTSS (0.44) | CTSSCTSKCTSLPPARAPPARG | |
| SCHEMBL22636134 | 1.00 | CTSS (0.44) | CTSSCTSKCTSLPPARAPPARG | |
| SCHEMBL29059461 | 0.94 | CTSK (0.43) | CTSSCTSKCTSLPPARAPPARG | |
| SCHEMBL1963143 | 0.94 | CTSK (0.43) | CTSSCTSKCTSLPPARAPPARG | |
| SCHEMBL2364176 | 0.94 | CTSK (0.43) | CTSSCTSKCTSLPPARAPPARG | |
| SCHEMBL2364166 | 0.94 | CTSK (0.43) | CTSSCTSKCTSLPPARAPPARG | |
| SCHEMBL2364175 | 0.94 | CTSK (0.43) | CTSSCTSKCTSLPPARAPPARG | |
| SCHEMBL8265511 | 0.93 | CTSK (0.43) | CTSSCTSKCTSLPPARAPPARG | |
| SCHEMBL3613122 | 0.93 | CTSK (0.43) | CTSSCTSKCTSLPPARAPPARG | |
| SCHEMBL13087991 | 0.88 | CTSL (0.44) | CTSSCTSKCTSLCTSBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004032834-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2004-04-22 | — | — | WO | disclosed |