Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA2 | Q9HCG7 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052893 | 1.00 | GBA2 (0.45) | GBA2SMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL15715693 | 0.91 | GBA2 (0.47) | GBA2SMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL15715217 | 0.88 | GBA2 (0.47) | GBA2SMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL25348025 | 0.88 | GBA2 (0.47) | GBA2SMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL18614400 | 0.86 | SMN1; SMN2 (0.40) | GBA2SMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL17674467 | 0.82 | GBA2 (0.44) | GBA2SMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL3391192 | 0.80 | CYP3A4 (0.42) | GBA2SMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL17154832 | 0.78 | LMNA (0.43) | GBA2SMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL7455919 | 0.78 | LMNA (0.43) | GBA2SMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL7455910 | 0.78 | LMNA (0.43) | GBA2SMN1; SMN2LMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7101935-A | — | — | None | — | — | JP | disclosed |
| WO-2004043366-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |
| JP-H07101935-A | CRYSTALLIZATION OF N-ALKOXYCARBONYLAMINO ACID ESTER | TOKUYAMA CORP | 1995-04-18 | — | — | JP | disclosed |