Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18288014 | 0.79 | HPGD (0.53) | MAPTCYP3A4HPGDKMT2ANPC1 | |
| SCHEMBL31493128 | 0.79 | HPGD (0.53) | MAPTCYP3A4HPGDKMT2ANPC1 | |
| SCHEMBL18288064 | 0.77 | ALOX15 (0.55) | CYP1A2PKMCYP2C19HPGDKMT2A | |
| SCHEMBL7952955 | 0.77 | KMT2A (0.69) | SMN1; SMN2KMT2AMEN1RXFP1BRD4 | |
| SCHEMBL7959710 | 0.76 | NR1H4 (0.62) | MAPTCYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL31281188 | 0.76 | TSHR (0.49) | MAPTCYP1A2CYP3A4CYP2C19HPGD | |
| SCHEMBL535683 | 0.76 | TSHR (0.49) | MAPTCYP1A2CYP3A4CYP2C19HPGD | |
| SCHEMBL9117716 | 0.76 | ALOX15 (0.46) | MAPTCYP1A2CYP3A4CYP2C19HPGD | |
| Hydrochloric Acid SCHEMBL22445134 | 0.75 | TSHR (0.47) | MAPTCYP1A2CYP3A4CYP2C19HPGD | |
| SCHEMBL18288083 | 0.75 | HPGD (0.53) | MAPTCYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | claimed |