Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TPMT | P51580 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9099466 | 0.83 | TTR (0.35) | TTRTSHRALOX15POLBHTT | |
| SCHEMBL10644829 | 0.76 | CA12 (0.47) | TSHRTPMTPOLBHTTMRGPRX4 | |
| SCHEMBL28436529 | 0.76 | ALDH1A1 (0.41) | TTRTSHRTPMTALOX15CA12 | |
| SCHEMBL28430472 | 0.74 | TRPV4 (0.50) | TTRTSHRTPMTALOX15HTT | |
| SCHEMBL474019 | 0.74 | TPMT (0.48) | TTRTSHRTPMTALOX15HCAR1 | |
| SCHEMBL29878149 | 0.74 | TPMT (0.48) | TTRTSHRTPMTALOX15MRGPRX4 | |
| SCHEMBL17914245 | 0.74 | ALDH1A1 (0.40) | TSHRTPMTALOX15HTTCA12 | |
| SCHEMBL7263572 | 0.74 | TTR (0.68) | TTRTSHRTPMTALOX15SRD5A2 | |
| SCHEMBL11556678 | 0.74 | TTR (0.76) | TTRTSHRTPMTALOX15SRD5A2 | |
| SCHEMBL10495674 | 0.74 | NOTUM (0.35) | TTRTSHRMRGPRX4AURKATPX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004013100-A2 | N-[PHENYL(PIPERIDIN-2-YL)METHYL]BENZAMIDE DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF IN THERAPY | SANOFI-AVENTIS (FR) | 2004-02-12 | — | — | WO | disclosed |
| EP-0600629-B1 | N-acetonylbenzamides and their use as fungicides | ROHM & HAAS (US) | 1996-05-08 | — | — | EP | disclosed |
| EP-0600629-A1 | N-acetonylbenzamides and their use as fungicides | ROHM AND HAAS COMPANY (US) | 1994-06-08 | — | — | EP | disclosed |
| US-5304572-A | N-acetonylbenzamides and their use as fungicides | ROHM AND HAAS COMPANY (US) | 1994-04-19 | — | — | US | disclosed |
| EP-0279698-A2 | Pesticidal compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-08-24 | — | — | EP | disclosed |