Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731094 | 0.74 | LMNA (0.57) | LMNA | |
| SCHEMBL30158523 | 0.74 | LMNA (0.57) | LMNA | |
| SCHEMBL13216335 | 0.74 | LMNA (0.57) | LMNA | |
| SCHEMBL202481 | 0.74 | LMNA (0.57) | LMNA | |
| SCHEMBL22987877 | 0.73 | NLRP3 (0.49) | P2RX7ALDH1A1MAPK1KMT2AHTT | |
| SCHEMBL21668593 | 0.73 | AR (0.48) | LMNA | |
| SCHEMBL14067288 | 0.72 | SLC22A12 (0.45) | P2RX7SLC22A12ALDH1A1MAPTMAPK1 | |
| SCHEMBL24989036 | 0.70 | AR (0.56) | LMNA | |
| SCHEMBL5355743 | 0.68 | LMNA (0.49) | LMNA | |
| SCHEMBL2722288 | 0.68 | SLC22A12 (0.33) | P2RX7SLC22A12ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039791-A1 | A PROCESS FOR THE PRODUCTION OF N-(4-CYANO-3-TRIFLUOROMETHYLPHENYL)-2,3-EPOXY-2-METHYLPROPANAMIDE | INSTYTUT FARMACEUTYCZNY (PL) | 2004-05-13 | — | — | WO | disclosed |