Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27512556 | 0.98 | LMNA (0.49) | LMNATSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL10694796 | 0.93 | TSHR (0.47) | LMNATSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL28996714 | 0.79 | TSHR (0.56) | LMNATSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL6753648 | 0.79 | TSHR (0.61) | LMNATSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL6024586 | 0.78 | TSHR (0.53) | LMNATSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL6024589 | 0.78 | TSHR (0.53) | LMNATSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL6920338 | 0.78 | MEN1 (0.44) | LMNATSHRALDH1A1MAPK1NPC1 | |
| SCHEMBL11149732 | 0.77 | TSHR (0.54) | LMNATSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL11772370 | 0.77 | TSHR (0.41) | LMNATSHRALDH1A1CYP3A4 | |
| SCHEMBL6057299 | 0.76 | LMNA (0.53) | LMNATSHRALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004035551-A2 | NOVEL FLUORINATED DYE STABILIZERS IN FLUORINATED DIELECTRIC SOLVENT | SIPIX IMAGING, INC. (US) | 2004-04-29 | — | — | WO | disclosed |