Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820242 | 0.93 | KDM4E (0.45) | PTGS2PTGS1ABCB1KDM4ETDP1 | |
| SCHEMBL6919614 | 0.89 | PTGS2 (0.46) | PTGS2ABCB1KDM4EMEN1KMT2A | |
| SCHEMBL6821172 | 0.88 | ELANE (0.45) | KDM4ELMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6817370 | 0.88 | P2RX4 (0.46) | PTGS2PTGS1ABCB1LMNACYP1A2 | |
| SCHEMBL6817298 | 0.87 | LMNA (0.61) | PTGS2PTGS1ABCB1KDM4EPPARG | |
| SCHEMBL6820214 | 0.85 | MEN1 (0.41) | PTGS2KDM4EPPARGMEN1KMT2A | |
| SCHEMBL3553237 | 0.85 | KDM4E (0.44) | KDM4ECYP1A2MEN1KMT2ATDP1 | |
| SCHEMBL6820272 | 0.84 | KDM4E (0.46) | ABCB1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL6821012 | 0.82 | KDM4E (0.41) | ABCB1KDM4ELMNACYP1A2CYP2D6 | |
| SCHEMBL6821037 | 0.80 | ABCB1 (0.43) | PTGS2ABCB1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |