Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820248 | 0.88 | PTGS2 (0.47) | KDM4ELMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6820229 | 0.88 | ALDH1A1 (0.43) | ELANEALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL6823561 | 0.88 | MEN1 (0.42) | ELANEALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL6817370 | 0.87 | P2RX4 (0.46) | ALDH1A1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6817298 | 0.86 | LMNA (0.61) | KDM4ELMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3567569 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNACYP1A2CYP2D6 | |
| SCHEMBL6817336 | 0.84 | ALDH1A1 (0.41) | ELANEALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL6820242 | 0.81 | KDM4E (0.45) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL6821012 | 0.79 | KDM4E (0.41) | ALDH1A1KDM4ELMNACYP1A2CYP2D6 | |
| SCHEMBL3561464 | 0.79 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |