Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820217 | 0.90 | AKR1B1 (0.33) | FPR2LMNAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL6820718 | 0.86 | KMT2A (0.36) | LMNAALDH1A1KDM4ETP53HSD11B1 | |
| SCHEMBL5966734 | 0.82 | KDM4E (0.35) | LMNAALDH1A1KDM4E | |
| SCHEMBL5963772 | 0.81 | AKR1B1 (0.33) | FPR2LMNAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL5963589 | 0.81 | SLC6A4 (0.38) | FPR2LMNAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL5963305 | 0.81 | SLC6A3 (0.39) | FPR2LMNAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL6820213 | 0.81 | AKR1B1 (0.39) | FPR2LMNAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL5001009 | 0.80 | GALR1 (0.33) | ALDH1A1AKR1B1PDE7A | |
| SCHEMBL6817306 | 0.80 | ALDH1A1 (0.38) | ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL5964210 | 0.79 | AKR1B1 (0.34) | FPR2LMNAALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326851-B1 | SUBSTITUTED DIPEPTIDES AS GROWTH HORMONE SECRETAGOGUES | LILLY CO ELI (US) | 2004-06-30 | — | — | EP | claimed |