Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5964212 | 0.80 | KMT2A (0.36) | KMT2ALMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5963390 | 0.78 | TSHR (0.34) | KMT2ALMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6820217 | 0.76 | AKR1B1 (0.33) | LMNAKDM4EALDH1A1HSD11B1 | |
| SCHEMBL5001155 | 0.68 | PTGS2 (0.37) | HTT | |
| SCHEMBL5966734 | 0.68 | KDM4E (0.35) | KMT2ALMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5963305 | 0.67 | SLC6A3 (0.39) | LMNAALDH1A1SLC6A2 | |
| SCHEMBL5004773 | 0.65 | ALDH1A1 (0.36) | KMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5963749 | 0.64 | FPR2 (0.34) | LMNASMN1; SMN2ALDH1A1SLC6A2 | |
| SCHEMBL6820982 | 0.62 | KDM4E (0.36) | LMNAKDM4EALDH1A1SLC6A2HSD11B1 | |
| SCHEMBL5964310 | 0.62 | ALDH1A1 (0.37) | KMT2ASMN1; SMN2ALDH1A1SLC6A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326851-B1 | SUBSTITUTED DIPEPTIDES AS GROWTH HORMONE SECRETAGOGUES | LILLY CO ELI (US) | 2004-06-30 | — | — | EP | claimed |